Do you want to find 'phenobarbital essay'? Here, you will find all the stuff.
Table of contents
- Phenobarbital essay in 2021
- Phenobarbital chemical name
- Phenobarbital mechanism of action
- List of phenobarbital drugs
- Phenobarbital uses
- Phenobarbital metabolism
- Phenobarbital contraindications
- Phenobarbital synthesis
Phenobarbital essay in 2021
Phenobarbital chemical name
Phenobarbital mechanism of action
List of phenobarbital drugs
Phenobarbital uses
Phenobarbital metabolism
Phenobarbital contraindications
Phenobarbital synthesis
What is the partition coefficient of a barbiturate?
As for Graph 2.0, a slow decrease is observed from pH 1.1 to pH 7.0, a steep decrease from pH 7.0 to pH 7.4, followed by a gradual decrease from pH 7.4 to pH 9.0. Partition coefficient, P is the ratio of a drug’s concentration in the octanol phase to its concentration in the aqueous phase at equilibrium with each other.
What is the ptrue value of phenobarbitone?
From the results section, Ptrue value at pH 1.1 is 7.74, whereas the literature value is 1.4. The comparison is made at pH 1.1 because phenobarbitone is present in its unionised form at low pH. However, the Ptrue value is much higher than the literature value.
How is phenobarbitone used in the treatment of epilepsy?
‘Phenobarbitone is a barbiturate used in the treatment of epilepsy. It helps to reduce seizure frequency and severity and may even stop seizures altogether.’ [1] ‘Phenobarbital works by acting on GABA receptors that in turn increase synaptic inhibition.
Last Update: Oct 2021